Study: Caffeine May Offset Some Health Risks Of Diets High In Fat, Sugar

Posted On: 12/31/2019

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CHAMPAIGN, IL -- OCS operators may want to spread the word that a new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides.

Rats that consumed the caffeine extracted from mate tea gained 16% less weight and accumulated 22% less body fat than rats that consumed decaffeinated mate tea, scientists at the University of Illinois found in a new study. Click here to read more.

The effects were similar with synthetic caffeine and that extracted from coffee.

Mate tea is an herbal beverage rich in phytochemicals, flavonoids and amino acids that’s consumed as a stimulant by people in southeastern Latin American countries. The amount of caffeine per serving in mate tea ranges from 65 to 130 milligrams, compared with 30 to 300 milligrams of caffeine in a cup of brewed coffee, according to the study.

For four weeks, the rats in the study ate a diet that contained 40% fat, 45% carbohydrate and 15% protein. They also ingested one of the forms of caffeine in an amount equivalent to that of a human who drinks four cups of coffee daily.

At the end of the four-week period, the percentage of lean body mass in the various groups of rats differed significantly. The rats that ingested caffeine from mate tea, coffee or synthetic sources accumulated less body fat than rats in the other groups.

The study, published recently in the Journal of Functional Foods, adds to a growing body of research that suggests mate tea may help fight obesity in addition to providing other beneficial health effects associated with the phenolic compounds, vitamins and flavonoids it contains.

“Considering the findings, mate tea and caffeine can be considered anti-obesity agents,” said Elvira Gonzalez de Mejia, a co-author of the study and director of the division of nutritional sciences at the University of Illinois. “The results of this research could be scaled to humans to understand the roles of mate tea and caffeine as potential strategies to prevent overweight and obesity, as well as the subsequent metabolic disorders associated with these conditions.”

In the rats, the accumulation of lipids in the adipocytes was significantly associated with greater body weight gain and increased body fat, according to the study.

To determine the mechanism of action, the scientists performed cell culture studies in which they

“The consumption of caffeine from mate or from other sources alleviated the negative impact of a high-fat, high-sucrose diet on body composition due to the modulation of certain lipogenic enzymes in both adipose tissue and the liver,” de Mejia said.

The work was funded by the University of Illinois Division of Nutritional Sciences.

 

TO YOUR HEALTH: In a study of rats, University of Illinois scientists found that caffeine limited weight gain and cholesterol production, despite a diet that was high in fat and sugar. Co-authors of the study included, from left, nutritional sciences professor Manabu T. Nakamura; Elvira Gonzalez de Mejia, director of the Division of Nutritional Sciences; and animal sciences professor Jan E. Novakofski.